The cees dekker Diaries
The cees dekker Diaries
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Spatial construction facilitates cooperation in the social Problem: empirical proof from the bacterial Neighborhood
Our group studies bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that will autonomously divide. Our primary interest lies in mobile division, chromatin construction, and spatial control.
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Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters
We build stage-of-treatment diagnostics take a look at of neglected tropical ailments inside useful resource-minimal options, according to Crspr/Cas9 detecting of pathogen’s DNA in body fluids.
Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: speedy electron relay to redox enzymes and zeptomole protein-film voltammetry
Considering the fact that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA restore proteins to DNA translocation as a result of nanopores. Not long ago his investigation has focused on researching cell division with bacteria https://www.ceesdekker.net on chip, though his best curiosity is in the way of acknowledging synthetic cells.
He also observed time to write down various books, send out almost forty thousand tweets and direct a successful investigation team at Delft University of Technological innovation. ‘It doesn’t feel like perform’, he suggests. ‘I’m just terribly curious.’
Understanding fundamental processes regulating the spatial and dynamic organisation of the DNA in live cells.
‘The fantastically subtle way wherein things in mother nature purpose in no way ceases to amaze me. If we resolve the puzzle of how life arrived into currently being, I count on that my amazement in the complexity of generation could have improved and with it my awe for the greatness of your Creator.’
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2001, discovery of single-electron transistors at room temperature according to nanotubes; realization of initial logic circuits with carbon nanotube gadgets; and discovery in the molecular construction of DNA fix enzymes with AFM
Developments in nanotechnology in the 1990s made constructing Digital products from one molecules a probability. Cees Dekker recounts how his staff made a home-temperature transistor depending on just one carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and solitary-molecule experiments